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Protein compatibility of selected cross-linking reactions for hydrogels

Hammer, Nadine, Brandl, Ferdinand, Kirchhof, Susanne, Messmann, Viktoria and Goepferich, Achim (2015) Protein compatibility of selected cross-linking reactions for hydrogels. Macromol. Biosci. 15 (3), pp. 405-413.

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Other URL: http://dx.doi.org/10.1002/mabi.201400379


The compatibility of selected cross-linking reactions with lysozyme is investigated. Michael-type additions of nucleophilic amino acids to maleimide, vinyl sulfone and acrylamide groups are detected by gel electrophoresis. The degree of modification depends on the polymer and the pH. Complete modification with more than five PEG chains is observed after incubation with mPEG5k-vinyl sulfone at pH ...


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Item type:Article
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich)
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Dewey Decimal Classification:600 Technology > 615 Pharmacy
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:31773
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