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Chromatin remodelers: from function to dysfunction

Längst, Gernot and Manelyte, Laura (2015) Chromatin remodelers: from function to dysfunction. Genes 2015 (6), pp. 299-324.

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Date of publication of this fulltext: 16 Jun 2015 09:54

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Other URL: http://www.mdpi.com/2073-4425/6/2/299


Abstract

Chromatin remodelers are key players in the regulation of chromatin accessibility and nucleosome positioning on the eukaryotic DNA, thereby essential for all DNA dependent biological processes. Thus, it is not surprising that upon of deregulation of those molecular machines healthy cells can turn into cancerous cells. Even though the remodeling enzymes are very abundant and a multitude of ...

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Item type:Article
Date:12 June 2015
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Prof. Dr. Gernot Längst
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.3390/genes6020299DOI
Keywords:chromatin remodeler; cancer; search mechanism; arrest model; non-coding RNA
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:31952
Owner only: item control page

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