Go to content
UR Home

Importin-β facilitates nuclear import of human GW proteins and balances cytoplasmic gene silencing protein levels

Meister, Gunter, Schindler, Susann G., Danner, Johannes, Kremmer, Elisabeth, Pfaff, Janina, Hannus, Stefan, Depping, Reinhard and Schraivogel, Daniel (2015) Importin-β facilitates nuclear import of human GW proteins and balances cytoplasmic gene silencing protein levels. Nucleic Acids Research 2015, pp. 1-15.

[img]
Preview
PDF
Download (9MB)
Date of publication of this fulltext: 19 Aug 2015 15:28

at publisher (via DOI)

Other URL: http://nar.oxfordjournals.org/content/early/2015/07/13/nar.gkv705.abstract


Abstract

MicroRNAs (miRNAs) guide Argonaute (Ago) proteins to distinct target mRNAs leading to translational repression and mRNA decay. Ago proteins interact with a member of the GW protein family, referred to as TNRC6A-C in mammals, which coordinate downstream gene-silencing processes. The cytoplasmic functions of TNRC6 and Ago proteins are reasonably well established. Both protein families are found in ...

plus


Export bibliographical data



Item type:Article
Date:13 July 2015
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie I
Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie I > Prof. Dr. Gunter Meister
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1093/nar/gkv705DOI
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:32360
Owner only: item control page

Downloads

Downloads per month over past year

  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons