The influence of age and sex on genetic associations with adult body size and shape: a large-scale genome-wide interaction study

URN to cite this document:: urn:nbn:de:bvb:355-epub-324447
DOI to cite this document:: 10.5283/epub.32444

Winkler, Thomas W. ; Heid, Iris M. ; Gorski, Mathias

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Date of publication of this fulltext: 02 Dec 2015 16:38

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Abstract

Genome-wide association studies (GWAS) have identified more than 100 genetic variants contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI, WHRadjBMI), a measure of body shape. Body size and shape change as people grow older and these changes differ substantially between men and women. To systematically screen for age- and/or sex-specific effects of genetic ...