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Clinical and pathological features of Burkitt lymphoma showing expression of BCL2 - an analysis including gene expression in formalin-fixed paraffin-embedded tissue

URN to cite this document:
urn:nbn:de:bvb:355-epub-327409
Masqué-Soler, Neus ; Szczepanowski, Monika ; Kohler, Christian W. ; Aukema, Sietse M. ; Nagel, Inga ; Richter, Julia ; Siebert, Reiner ; Spang, Rainer ; Burkhardt, Birgit ; Klapper, Wolfram
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Date of publication of this fulltext: 12 Nov 2015 13:11


Abstract

The differential diagnosis between Burkitt lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL) can be challenging. BL has been reported to express less BCL2 than DLBCL, but this issue has not been analysed systematically. BL expressing BCL2 can be considered to be MYC/BCL2 co-expressors, a feature that is associated with poorer outcome in DLBCL but that has not been correlated with outcome in ...

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