Metabolic plasticity of human T cells: Preserved cytokine production under glucose deprivation or mitochondrial restriction, but 2-deoxy-glucose affects effector functions.
Renner, Kathrin, Geiselhöringer, Anna-Lena, Fante, Matthias, Bruss, Christina, Färber, Stephanie, Schönhammer, Gabriele, Peter, Katrin, Singer, Katrin, Andreesen, Reinhard, Hoffmann, Petra, Oefner, Peter J.
, Herr, Wolfgang and Kreutz, Marina
(2015)
Metabolic plasticity of human T cells: Preserved cytokine production under glucose deprivation or mitochondrial restriction, but 2-deoxy-glucose affects effector functions.
Eur J Immunol 45 (9), pp. 2504-2516.
Date of publication of this fulltext: 13 Nov 2015 14:45
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| Item type | Article | ||||||
| Journal or Publication Title | Eur J Immunol | ||||||
| Publisher: | WILEY | ||||||
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| Place of Publication: | HOBOKEN | ||||||
| Volume: | 45 | ||||||
| Number of Issue or Book Chapter: | 9 | ||||||
| Page Range: | pp. 2504-2516 | ||||||
| Date | 20 July 2015 | ||||||
| Institutions | Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Funktionelle Genomik (Prof. Oefner) Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie) Leibniz Institute for Immunotherapy (LIT) | ||||||
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| Keywords | LYMPHOCYTE ACTIVATION; IMMUNE CELLS; MEMORY; GLYCOLYSIS; GLUTAMINE; 2-DEOXY-D-GLUCOSE; INHIBITION; MIGRATION; REQUIRES; TARGET; 2-deoxy-glucose; ATP; Cytokines; Glucose deprivation; Human CD4 T cells; Human CD8 T cells; Metabolism; Mitochondrial inhibition | ||||||
| Dewey Decimal Classification | 600 Technology > 610 Medical sciences Medicine | ||||||
| Status | Published | ||||||
| Refereed | Yes, this version has been refereed | ||||||
| Created at the University of Regensburg | Yes | ||||||
| Item ID | 32756 |
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