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In vitro myotoxic effects of bupivacaine on rhabdomyosarcoma cells, immortalized and primary muscle cells

Metterlein, Thomas, Hoffmann, Petra, Späth, Ruth, Gruber, Michael, Graf, Bernhard M. and Zing, Wolfgang (2015) In vitro myotoxic effects of bupivacaine on rhabdomyosarcoma cells, immortalized and primary muscle cells. Cancer Cell International 15 (75), pp. 1-6.

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Date of publication of this fulltext: 11 Dec 2015 11:59

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Other URL: http://www.cancerci.com/content/15/1/75


Abstract

Background Rhabdomyosarcoma is a rare malignant skeletal muscle tumor. It mainly occurs in children and young adults and has an unsatisfactory prognosis. Prior studies showed a direct myotoxic effect of bupivacaine on differentiated muscle cells in vitro and in vivo. Exact mechanisms of this myotoxicity are still not fully understood, but a myotoxic effect on malignant muscle tumor cells has not ...

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Item type:Article
Date:29 July 2015
Institutions:Medicine > Lehrstuhl für Anästhesiologie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1186/s12935-015-0229-6DOI
Keywords:Myotoxicity; Rhabdomyosarcoma; Bupivacaine; Cell culture
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:33041
Owner only: item control page

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