Effects of ketamine, s-ketamine, and MK 801 on proliferation, apoptosis, and necrosis in pancreatic cancer cells

URN to cite this document:: urn:nbn:de:bvb:355-epub-330420
DOI to cite this document:: 10.5283/epub.33042

Malsy, Manuela ; Gebhardt, Kristina ; Gruber, Michael ; Wiese, Christoph ; Graf, Bernhard M. ; Bundscherer, Anika Christin

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Date of publication of this fulltext: 11 Dec 2015 12:19

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Abstract

Background Adenocarcinoma of the pancreas is one of the most aggressive cancer diseases affecting the human body. The oncogenic potential of this type of cancer is mainly characterized by its extreme growth rate triggered by the activation of signaling cascades. Modern oncological treatment strategies aim at efficiently modulating specific signaling and transcriptional pathways. Recently, ...