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Fluoxetine requires the endfeet protein aquaporin-4 to enhance plasticity of astrocyte processes

Neumann, Inga D., Di Benedetto, Barbara, Malik, Victoria A., Begum, Salina, Jablonowski, Lena, Gómez-González, Gabriela B. and Rupprecht, Rainer (2016) Fluoxetine requires the endfeet protein aquaporin-4 to enhance plasticity of astrocyte processes. Frontiers in Cellular Neuroscience 10 (8), pp. 1-12.

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Date of publication of this fulltext: 04 Feb 2016 12:55

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Other URL: http://journal.frontiersin.org/article/10.3389/fncel.2016.00008/abstract


Morphological alterations in astrocytes are characteristic for post mortem brains of patients affected by major depressive disorder (MDD). Recently, a significant reduction in the coverage of blood vessels (BVs) by aquaporin-4 (AQP-4)-positive astrocyte endfeet has been shown in the prefrontal cortex (PFC) of MDD patients, suggesting that either alterations in the morphology of endfeet or in ...


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Item type:Article
Date:2 February 2016
Institutions:Biology, Preclinical Medicine > Institut für Zoologie > Tierphysiologie/Neurobiologie (Prof. Dr. Inga Neumann)
Projects:Open Access Publizieren (DFG)
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Keywords:fluoxetine, astrocytes, glia-vasculature interface, plasticity, aquaporin-4
Dewey Decimal Classification:500 Science > 590 Zoological sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:33259
Owner only: item control page


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