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Schreml, Stephan ; Haverkamp, Sonja ; Evert, Katja ; Schröder, Josef

Nodular Cutaneous Amyloidosis Resembling a Giant Tumor

Schreml, Stephan, Haverkamp, Sonja, Evert, Katja and Schröder, Josef (2016) Nodular Cutaneous Amyloidosis Resembling a Giant Tumor. Case Reports in Dermatology 8 (1), pp. 22-25.

Date of publication of this fulltext: 18 Feb 2016 16:40
Article
DOI to cite this document: 10.5283/epub.33332


Abstract

A 79-year-old man presented with a large tumor on the left side of his head, which had grown over 5 years. Regional lymph nodes were impalpable and computed tomography revealed no signs of bone infiltration. Histology showed that the entire dermis was filled with amorphous eosinophilic material. Immunohistochemistry was negative for cytokeratin, but showed that the dermis and parts of the ...

A 79-year-old man presented with a large tumor on the left side of his head, which had grown over 5 years. Regional lymph nodes were impalpable and computed tomography revealed no signs of bone infiltration. Histology showed that the entire dermis was filled with amorphous eosinophilic material. Immunohistochemistry was negative for cytokeratin, but showed that the dermis and parts of the subcutis were filled with amyloid consisting of immunoglobulin light chains. There were no signs of paraproteinemia or underlying plasmocytoma. In electron microscopy, the typical amyloid fibrils were found. The tumor was completely removed via curettage. At 1-year follow-up, the patient was doing fine with no signs of relapse or systemic disease.



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Details

Item typeArticle
Journal or Publication TitleCase Reports in Dermatology
Publisher:Kagerer
Volume:8
Number of Issue or Book Chapter:1
Page Range:pp. 22-25
Date3 February 2016
InstitutionsMedicine > Lehrstuhl für Dermatologie und Venerologie
Identification Number
ValueType
10.1159/000443950DOI
Dewey Decimal Classification600 Technology > 610 Medical sciences Medicine
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgYes
URN of the UB Regensburgurn:nbn:de:bvb:355-epub-333321
Item ID33332

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