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A novel set of symmetric methylene blue derivatives exhibits effective bacteria photokilling – a structure–response study

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Gollmer, Anita ; Felgenträger, Ariane ; Bäumler, Wolfgang ; Maisch, Tim ; Späth, Andreas
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Date of publication of this fulltext: 24 Feb 2016 14:51


This study focuses on the structure–response relationship of symmetrically substituted phenothiazinium dyes. Four hydrophilic derivatives with the ability of additional hydrogen bonding (5, 6) or additional electrostaticinteraction (3, 4) were synthesized, photophysically characterized and compared to the parent compound methylene blue (MB, 1) and a lipophilic derivative (2) without additional ...


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