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Use of Selective Cyclooxygenase-2 Inhibitors, Other Analgesics, and Risk of Glioma

URN to cite this document:
urn:nbn:de:bvb:355-epub-335947
DOI to cite this document:
10.5283/epub.33594
Seliger, Corinna ; Meier, Christoph R. ; Becker, Claudia ; Jick, Susan S. ; Bogdahn, Ulrich ; Hau, Peter ; Leitzmann, Michael F.
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Date of publication of this fulltext: 06 Apr 2016 08:41


Abstract

Background Selective cyclooxygenase-2 (COX-2) inhibitors are analgesic, antipyretic, and anti-inflammatory drugs. They have been found to inhibit the development of glioma in laboratory investigations. Whether these drugs reduce the risk of glioma incidence in humans is unknown. Methods We conducted a matched case-control analysis using the U.K.-based Clinical Practice Research Datalink (CPRD). ...

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