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Urinary metabolite quantification employing 2D NMR spectroscopy

Gronwald, Wolfram, Klein, M. S., Kaspar, Hannelore, Fagerer, S. R., Nürnberger, N., Dettmer, Katja, Bertsch, T. and Oefner, Peter J. (2008) Urinary metabolite quantification employing 2D NMR spectroscopy. Anal. Chem. 80 (23), pp. 9288-9297.

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Other URL: http://pubs.acs.org/doi/full/10.1021/ac801627c#_i11


Two-dimensional (2D) nuclear magnetic resonance (NMR) spectroscopy is a fairly novel method for the quantification of metabolites in biological fluids and tissue extracts. We show in this contribution that, compared to 1D 1H spectra, superior quantification of human urinary metabolites is obtained from 2D 1H−13C heteronuclear single-quantum correlation (HSQC) spectra measured at natural ...


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Item type:Article
Date:December 2008
Institutions:Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Funktionelle Genomik (Prof. Oefner)
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Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:33608
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