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Impedance-Based Analysis of the Cellular Response to Microparticles: Theory, Assay Development and Model Study

Sperber, Michaela (2017) Impedance-Based Analysis of the Cellular Response to Microparticles: Theory, Assay Development and Model Study. PhD, Universität Regensburg.

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Date of publication of this fulltext: 20 Feb 2017 06:14

Abstract (English)

This thesis provides a model study on the information content of multimodal impedance-based assays to assess the impact of microscale particles on cell physiology of mammalian cells. In three main chapters, different approaches to this topic are presented and discussed: The first chapter focused on the simulation of several scenarios within cell-based assays. These simulations are all based on ...

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Translation of the abstract (German)

Die vorliegende Arbeit ist eine Modellstudie, die unter Einsatz multimodaler, labelfreier impedanz-basierter Sensorik eine sequentielle Analyse des Einflusses von Mikropartikeln auf die Zellphysiologie von adhärenten Zellen ermöglicht. Die Studie gliedert sich in drei verschiedene Projekte. Im ersten Kapitel wurden Impedanzspektren unter Zuhilfenahme des bekannten ECIS Modells von Giaever und ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:19 February 2017
Referee:Prof. Dr. Joachim Wegener
Date of exam:19 February 2016
Institutions:Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Bioanalytik und Biosensorik (Prof. Joachim Wegener)
Keywords:Impedanzanalyse, adhärente Zellen, Mikropartikel/ impedance analysis, adherent cells, microparticles
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:33630
Owner only: item control page

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