Quantitative Imaging of D-2-Hydroxyglutarate in Selected Histological Tissue Areas by a Novel Bioluminescence Technique

URN to cite this document:: urn:nbn:de:bvb:355-epub-338844
DOI to cite this document:: 10.5283/epub.33884

Voelxen, N. F. ; Walenta, S. ; Proescholdt, Martin A. ; Dettmer, Katja

; Pusch, S.

; Mueller-Klieser, W.

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Date of publication of this fulltext: 16 Jun 2016 08:55

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Abstract

Patients with malignant gliomas have a poor prognosis with average survival of less than 1 year. Whereas in other tumor entities the characteristics of tumor metabolism are successfully used for therapeutic approaches, such developments are very rare in brain tumors, notably in gliomas. One metabolic feature characteristic of gliomas, in particular diffuse astrocytomas and oligodendroglial ...