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Quantitative Imaging of D-2-Hydroxyglutarate in Selected Histological Tissue Areas by a Novel Bioluminescence Technique

Voelxen, N. F., Walenta, S., Proescholdt, Martin A., Dettmer, Katja, Pusch, S. and Mueller-Klieser, W. (2016) Quantitative Imaging of D-2-Hydroxyglutarate in Selected Histological Tissue Areas by a Novel Bioluminescence Technique. Frontiers in Oncology 6, p. 46.

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Date of publication of this fulltext: 16 Jun 2016 08:55

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Other URL: http://journal.frontiersin.org/article/10.3389/fonc.2016.00046/full


Abstract

Patients with malignant gliomas have a poor prognosis with average survival of less than 1 year. Whereas in other tumor entities the characteristics of tumor metabolism are successfully used for therapeutic approaches, such developments are very rare in brain tumors, notably in gliomas. One metabolic feature characteristic of gliomas, in particular diffuse astrocytomas and oligodendroglial ...

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Item type:Article
Date:7 March 2016
Institutions:Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Funktionelle Genomik (Prof. Oefner)
Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Statistische Bioinformatik (Prof. Spang)
Identification Number:
ValueType
10.3389/fonc.2016.00046DOI
Keywords:D-2 hydroxyglutarate, IDH mutations, bioluminescence imaging, oncometabolite, glioblastoma
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:33884
Owner only: item control page

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