Abstract
The structural information gained from the study of the chiral building block (R)-(-)-4-(3,4-dichlorophenyl)-4-(2-pyridyl)-butanoic acid-L-(-)-ephedrine [methyl(1-hydroxy-1-phenyl-prop-2-yl)ammonium 4-(3,4-dichlorophenyl)-4-(2-pyridyl)-butanoate], C10H16NO+. C15H12Cl2NO2-, can be used to deduce the absolute configuration of highly potent arpromidine-type histamine H-2 receptor agonists, as the ...
Abstract
The structural information gained from the study of the chiral building block (R)-(-)-4-(3,4-dichlorophenyl)-4-(2-pyridyl)-butanoic acid-L-(-)-ephedrine [methyl(1-hydroxy-1-phenyl-prop-2-yl)ammonium 4-(3,4-dichlorophenyl)-4-(2-pyridyl)-butanoate], C10H16NO+. C15H12Cl2NO2-, can be used to deduce the absolute configuration of highly potent arpromidine-type histamine H-2 receptor agonists, as the chiral butanoic acid can be converted to (R)-(-)-3-(3,4-dichlorophenyl)-3-(2-pyridyl)propylamine and to the corresponding R-configured arpromidine analogue.
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