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Tailoring drug release profile of low-molecular-weight hydrogels by supramolecular co-assembly and thiol–ene orthogonal coupling

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Díaz Díaz, David ; Morin, Emmanuelle ; Schön, Eva M. ; Budin, Ghyslain ; Wagner, Alain ; Remy, Jean-Serge
License: Allianz- bzw. Nationallizenz
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Date of publication of this fulltext: 21 Jul 2016 05:52


We describe a general user-friendly platform for fine-tuning the drug release properties of low-molecular-weight hydrogels by a combination of supramolecular co-assembly of complementary molecular structures and controlled photochemical thiol–ene cross-linking. Other critical features such as thermomechanical stability and morphology of the nanostructured hydrogels are also tailored by this approach.

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