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Tailoring drug release profile of low-molecular-weight hydrogels by supramolecular co-assembly and thiol–ene orthogonal coupling
Díaz Díaz, David, Morin, Emmanuelle, Schön, Eva M., Budin, Ghyslain, Wagner, Alain
and Remy, Jean-Serge
(2011)
Tailoring drug release profile of low-molecular-weight hydrogels by supramolecular co-assembly and thiol–ene orthogonal coupling.
Journal of Materials Chemistry 21, pp. 641-644.
Date of publication of this fulltext: 21 Jul 2016 05:52
Article
DOI to cite this document: 10.5283/epub.34110
Abstract
We describe a general user-friendly platform for fine-tuning the drug release properties of low-molecular-weight hydrogels by a combination of supramolecular co-assembly of complementary molecular structures and controlled photochemical thiol-ene cross-linking. Other critical features such as thermomechanical stability and morphology of the nanostructured hydrogels are also tailored by this approach.
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| Item type | Article | ||||
| Journal or Publication Title | Journal of Materials Chemistry | ||||
| Publisher: | ROYAL SOC CHEMISTRY | ||||
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| Place of Publication: | CAMBRIDGE | ||||
| Volume: | 21 | ||||
| Page Range: | pp. 641-644 | ||||
| Date | 2011 | ||||
| Institutions | Chemistry and Pharmacy > Institut für Organische Chemie > Arbeitskreis Prof. Dr. David Díaz Díaz Chemistry and Pharmacy > Institut für Organische Chemie > Arbeitskreis Prof. Dr. David Díaz Díaz | ||||
| Identification Number |
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| Keywords | SELF-ASSEMBLED HYDROGEL; CLICK CHEMISTRY; AMINO-ACID; TERMINAL ALKYNES; GEL; CYCLOADDITION; DERIVATIVES; ENTRAPMENT; ORGANOGELS; DIPEPTIDE; | ||||
| Dewey Decimal Classification | 500 Science > 540 Chemistry & allied sciences | ||||
| Status | Published | ||||
| Refereed | Yes, this version has been refereed | ||||
| Created at the University of Regensburg | Partially | ||||
| URN of the UB Regensburg | urn:nbn:de:bvb:355-epub-341108 | ||||
| Item ID | 34110 |
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