Wolf, Cornelia, Schulze, Frank R., Buschauer, Armin and Schunack, Walter (1998) Combined histamine H_1/H_2 receptor antagonists: Part II. Pharmacological hybrids with pheniramine- and tiotidine-like substructures,. European Journal of Pharmaceutical Sciences 6 (3), pp. 187-196.
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Abstract
Hybrid molecules combining the crucial structural features of both pheniramine-type histamine H1 receptor antagonists and guanidinothiazole-type H2 receptor antagonists have been synthesized and tested for in vitro pharmacological activity at the isolated ileum and the spontaneously beating right atrium of the guinea-pig. In the title compounds the basic side chain nitrogen of the H1 antagonist ...
Export bibliographical data
| Item type: | Article | ||||
|---|---|---|---|---|---|
| Date: | 1998 | ||||
| Institutions: | Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer) | ||||
| Identification Number: |
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| Keywords: | Histamine; Histamine H1 receptor antagonists; Histamine H2 receptor antagonists; Pheniramine; 2-Guanidinothiazole | ||||
| Dewey Decimal Classification: | 500 Science > 570 Life sciences 500 Science > 540 Chemistry & allied sciences | ||||
| Status: | Published | ||||
| Refereed: | Yes, this version has been refereed | ||||
| Created at the University of Regensburg: | Partially | ||||
| Item ID: | 3418 |
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