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Incremental parameter evaluation from incomplete data with application to the population pharmacology of anticoagulants

Vlad, M. O., Corlan, A. D., Moran, F., Oefner, Peter J. and Ross, J. (2008) Incremental parameter evaluation from incomplete data with application to the population pharmacology of anticoagulants. Proceedings of the National Academy of Sciences of the United States of America (PNAS 105 (12), pp. 4627-4632.

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Abstract

We develop a method for parameter evaluation from incomplete data. Improved estimates of the desired parameters are evaluated step by step, from experiment to experiment by using both Bayesian and informational methods. We make dynamical, improved predictions while the experiments are still going on and keep and interpret information about local fluctuations, which is lost on applying global ...

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Item type:Article
Date:25 March 2008
Institutions:Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Funktionelle Genomik (Prof. Oefner)
Identification Number:
ValueType
18353988PubMed ID
10.1073/pnas.0711508105DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:34323
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