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Incremental parameter evaluation from incomplete data with application to the population pharmacology of anticoagulants

Vlad, M. O. ; Corlan, A. D. ; Moran, F. ; Oefner, Peter J. ; Ross, J.



Abstract

We develop a method for parameter evaluation from incomplete data. Improved estimates of the desired parameters are evaluated step by step, from experiment to experiment by using both Bayesian and informational methods. We make dynamical, improved predictions while the experiments are still going on and keep and interpret information about local fluctuations, which is lost on applying global ...

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