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CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles

Beier, D., Hau, Peter, Proescholdt, M., Lohmeier, A., Wischhusen, J., Oefner, Peter J., Aigner, L., Brawanski, Alexander, Bogdahn, Ulrich and Beier, Christoph P. (2007) CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles. Cancer Research 67 (9), pp. 4010-4015.

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Other URL: http://cancerres.aacrjournals.org/content/67/9/4010


Abstract

Although glioblastomas show the same histologic phenotype, biological hallmarks such as growth and differentiation properties vary considerably between individual cases. To investigate whether different subtypes of glioblastomas might originate from different cells of origin, we cultured tumor cells from 22 glioblastomas under medium conditions favoring the growth of neural and cancer stem cells ...

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Item type:Article
Date:1 May 2007
Institutions:Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Funktionelle Genomik (Prof. Oefner)
Medicine > Lehrstuhl für Neurochirurgie
Medicine > Lehrstuhl für Neurologie
Identification Number:
ValueType
17483311PubMed ID
10.1158/0008-5472.CAN-06-4180DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:34369
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