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Modificomics: posttranslational modifications beyond protein phosphorylation and glycosylation

Reinders, Jörg ; Sickmann, Albert



Abstract

Posttranslational modifications of proteins possess key functions in the regulation of various cellular processes. While they facilitate fast, location-specific and transient reactions to changing conditions in the first place they enhance the already high complexity of a cellular proteome by orders of magnitude. Furthermore, they can utterly alter the properties of the modified protein, thus ...

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