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Genome sequencing and comparative analysis of Saccharomyces cerevisiae strain YJM789

Wei, W. ; McCusker, J. H. ; Hyman, R. W. ; Jones, T. ; Ning, Y. ; Cao, Z. ; Gu, Z. ; Bruno, D. ; Miranda, M. ; Nguyen, M. ; Wilhelmy, J. ; Komp, C. ; Tamse, R. ; Wang, X. ; Jia, P. ; Luedi, P. ; Oefner, Peter J. ; David, L. ; Dietrich, F. S. ; Li, Y. ; Davis, R. W. ; Steinmetz, L. M.



Abstract

We sequenced the genome of Saccharomyces cerevisiae strain YJM789, which was derived from a yeast isolated from the lung of an AIDS patient with pneumonia. The strain is used for studies of fungal infections and quantitative genetics because of its extensive phenotypic differences to the laboratory reference strain, including growth at high temperature and deadly virulence in mouse models. Here ...

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