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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-344687
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.34468
Zusammenfassung
Sepsis-induced immune reactions are reduced in TNF receptor 2 (TNFR2)-deficient mice as previously shown. In order to elucidate the underlying mechanisms, the functional integrity of myeloid cells of TNFR2-deficient mice was analyzed and compared to wild type (WT) mice. The capacity of dendritic cells to produce IL-12 was strongly impaired in TNF-deficient mice, mirroring impaired production of ...
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