LTβR expression on hematopoietic cells regulates acute inflammation and influences maturation of myeloid subpopulations

URN to cite this document:: urn:nbn:de:bvb:355-epub-344759
DOI to cite this document:: 10.5283/epub.34475

Wege, Anja K. ; Huber, Barbara ; Wimmer, Nadin ; Männel, Daniela N. ; Hehlgans, Thomas

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Date of publication of this fulltext: 26 Aug 2016 05:25

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Abstract

Lymphotoxin beta-receptor (LT beta R) is involved in the formation and maintenance of secondary lymphoid structures, as well as in the regulation of inflammatory responses. Because LT beta R lymphoid structure formation continues to develop in infants, we compared two different chimera models: one using adult mice and the other using a transplantation model of neonatal mice. To elucidate the ...