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LTβR expression on hematopoietic cells regulates acute inflammation and influences maturation of myeloid subpopulations

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Wege, Anja K. ; Huber, Barbara ; Wimmer, Nadin ; Männel, Daniela N. ; Hehlgans, Thomas
License: Allianz- bzw. Nationallizenz
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Date of publication of this fulltext: 26 Aug 2016 05:25


Lymphotoxin beta-receptor (LTβR) is involved in the formation and maintenance of secondary lymphoid structures, as well as in the regulation of inflammatory responses. Because LTβR lymphoid structure formation continues to develop in infants, we compared two different chimera models: one using adult mice and the other using a transplantation model of neonatal mice. To elucidate the function of ...


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