LTβR expression on hematopoietic cells regulates acute inflammation and influences maturation of myeloid subpopulations

URN to cite this document:: urn:nbn:de:bvb:355-epub-344759
DOI to cite this document:: 10.5283/epub.34475

Wege, Anja K. ; Huber, Barbara ; Wimmer, Nadin ; Männel, Daniela N. ; Hehlgans, Thomas

Preview

License: Allianz- bzw. Nationallizenz
PDF - Published Version
(742kB)

Date of publication of this fulltext: 26 Aug 2016 05:25

Alternative links to fulltext:DOI

Details

Preview

Export bibliographical data

Abstract

Lymphotoxin beta-receptor (LTβR) is involved in the formation and maintenance of secondary lymphoid structures, as well as in the regulation of inflammatory responses. Because LTβR lymphoid structure formation continues to develop in infants, we compared two different chimera models: one using adult mice and the other using a transplantation model of neonatal mice. To elucidate the function of ...