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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-344947
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.34494
Zusammenfassung
The human cytomegalovirus (hCMV) major immediate-early 1 protein (IE1) is best known for activating transcription to facilitate viral replication. Here we present transcriptome data indicating that IE1 is as significant a repressor as it is an activator of host gene expression. Human cells induced to express IE1 exhibit global repression of IL6- and oncostatin M-responsive STAT3 target genes. ...
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