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Assessment of Different Expression Strategies for the Production of a Recombinant Lipoprotein Vaccine in Plants

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DOI to cite this document:
Hennig, A. ; Reinders, Yvonne ; Giritch, A. ; Reinders, Jörg ; Warzecha, H.
License: Creative Commons Attribution Non-commercial 4.0
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Date of publication of this fulltext: 07 Sep 2016 08:03


The ability of plants to serve as a production system for bacterial lipoprotein vaccines has been investigated. First, the effect of high-level expression of the Borrelia burgdorferi outer membrane protein A (OspA), a prototype vaccine against Lyme disease, has been examined by a proteomics approach. Analysis by 2D-PAGE of wild type tobacco plants and transplastomic plants accumulating ...


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