Hennig, A., Reinders, Yvonne, Giritch, A., Reinders, Jörg and Warzecha, H. (2008) Assessment of Different Expression Strategies for the Production of a Recombinant Lipoprotein Vaccine in Plants. Open Biotechnology Journal 2, pp. 51-55.
| License: Creative Commons Attribution Non-commercial 4.0 PDF - Published Version Download (596kB) |
Abstract
The ability of plants to serve as a production system for bacterial lipoprotein vaccines has been investigated. First, the effect of high-level expression of the Borrelia burgdorferi outer membrane protein A (OspA), a prototype vaccine against Lyme disease, has been examined by a proteomics approach. Analysis by 2D-PAGE of wild type tobacco plants and transplastomic plants accumulating ...
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| Item type: | Article | ||||
|---|---|---|---|---|---|
| Date: | 2008 | ||||
| Institutions: | Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Funktionelle Genomik (Prof. Oefner) | ||||
| Identification Number: |
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| Keywords: | Plant vaccine, lipoprotein, protein palmitoylation, outer surface protein A, chloroplast transformation | ||||
| Dewey Decimal Classification: | 500 Science > 570 Life sciences 600 Technology > 610 Medical sciences Medicine | ||||
| Status: | Published | ||||
| Refereed: | Yes, this version has been refereed | ||||
| Created at the University of Regensburg: | Yes | ||||
| Item ID: | 34537 |
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