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Assessment of Different Expression Strategies for the Production of a Recombinant Lipoprotein Vaccine in Plants

Hennig, A., Reinders, Yvonne, Giritch, A., Reinders, Jörg and Warzecha, H. (2008) Assessment of Different Expression Strategies for the Production of a Recombinant Lipoprotein Vaccine in Plants. Open Biotechnology Journal 2, pp. 51-55.

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Abstract

The ability of plants to serve as a production system for bacterial lipoprotein vaccines has been investigated. First, the effect of high-level expression of the Borrelia burgdorferi outer membrane protein A (OspA), a prototype vaccine against Lyme disease, has been examined by a proteomics approach. Analysis by 2D-PAGE of wild type tobacco plants and transplastomic plants accumulating ...

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Item type:Article
Date:2008
Institutions:Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Funktionelle Genomik (Prof. Oefner)
Identification Number:
ValueType
10.2174/1874070700802010051DOI
Keywords:Plant vaccine, lipoprotein, protein palmitoylation, outer surface protein A, chloroplast transformation
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:34537
Owner only: item control page

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