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Expression of BMP and Actin Membrane Bound Inhibitor (BAMBI) is increased during terminal differentiation of MSCs

Pfeifer, Christian G., Karl, Alexandra, Berner, Arne, Zellner, Johannes, Schmitz, Paul, Loibl, Markus, Koch, Matthias, Angele, Peter, Nerlich, Michael and Mueller, Michael B. (2016) Expression of BMP and Actin Membrane Bound Inhibitor (BAMBI) is increased during terminal differentiation of MSCs. Stem Cells International 2016, pp. 1-9.

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Date of publication of this fulltext: 29 Nov 2016 12:14

at publisher (via DOI)

Other URL: https://www.hindawi.com/journals/sci/2016/2685147/


Abstract

Chondrogenic differentiating mesenchymal stem cells (MSCs) are mimicking embryonal endochondral ossification and become hypertrophic. BMP (bone morphogenetic protein) and Activin Membrane Bound Inhibitor (BAMBI) is a pseudoreceptor that regulates the activity of transforming growth factor-β (TGF-β) and BMP signalling during chondrogenesis. Both TGF-β and BMP signalling are regulators of ...

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Item type:Article
Date:27 September 2016
Institutions:Medicine > Lehrstuhl für Unfallchirurgie
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1155/2016/2685147DOI
Keywords:mesenchymal stem cells, chondrogenesis, terminal differentiation, TGF-beta, signalling, receptor, BAMBI, BMP
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:34732
Owner only: item control page

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