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Impedance Analysis of Epithelial Barrier Function: New Devices and Assays

Hajek, Kathrin (2017) Impedance Analysis of Epithelial Barrier Function: New Devices and Assays. PhD, Universität Regensburg.

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Date of publication of this fulltext: 16 Jul 2018 07:50

Abstract (English)

Dynamics and alterations of cellular barriers (epithelial or endothelial tissue) are studied in detail under physiological and pathological conditions in vitro. In order to do so, interfacial tissue is commonly cultured on permeable growth substrates to mimic in vivo like conditions. Impedimetric techniques (transfilter resistance measurements, electric cell substrate impedance sensing: ECIS) ...

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Translation of the abstract (German)

Zahlreiche Studien befassen sich mit der Charakterisierung und der Dynamik Barriere bildender Zellschichten (Zellen der Haut, der Darm- oder Gefäßauskleidung). In vitro Modelle dienen dabei der detaillierten Untersuchung diverser Grenzflächengeweben unter physiologischen sowie pathologischen Bedingungen. In der Regel werden dafür immortalisierte Zelllinien, seltener auch primär isolierte Zellen, ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:12 December 2017
Referee:Prof. Dr. Joachim Wegener
Date of exam:2 December 2016
Institutions:Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Bioanalytik und Biosensorik (Prof. Joachim Wegener)
Keywords:impedance analysis, epithelial barrier function, TEER, permeability
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:34979
Owner only: item control page

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