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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-350495
- DOI to cite this document:
- 10.5283/epub.35049
Abstract
Background Inhibitors of the renin angiotensin system and neprilysin (RAS-/NEP-inhibitors) proved to be extraordinarily beneficial in systolic heart failure. Furthermore, compelling evidence exists that impaired mitochondrial pathways are causatively involved in progressive left ventricular (LV) dysfunction. Consequently, we aimed to assess whether RAS-/NEP-inhibition can attenuate mitochondrial ...

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