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Vascular Alterations in a Murine Model of Acute Graft-Versus-Host Disease Are Associated With Decreased Serum Levels of Adiponectin and an Increased Activity and Vascular Expression of Indoleamine 2,3-Dioxygenase

Schmid, Peter M., Bouazzaoui, Karin, Schmid, Karin, Birner, Christoph, Schach, Christian, Maier, Lars, Holler, Ernst and Endemann, Dierk H. (2016) Vascular Alterations in a Murine Model of Acute Graft-Versus-Host Disease Are Associated With Decreased Serum Levels of Adiponectin and an Increased Activity and Vascular Expression of Indoleamine 2,3-Dioxygenase. Cell Transplantation 2016 (25), pp. 2051-2062.

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Date of publication of this fulltext: 17 Jan 2017 15:30

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Other URL: http://www.ingentaconnect.com/content/cog/ct/2016/00000025/00000011/art00011


Abstract

Graft-versus-host disease (GVHD) is the limiting complication after bone marrow transplantation (BMT), and its pathophysiology seems to be highly influenced by vascular factors. Our study aimed at elucidating possible mechanisms involved in vascular GVHD. For this purpose, we used a fully MHC-mismatched model of BALB/c mice conditioned according to two different intensity protocols with total ...

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Item type:Article
Date:11 November 2016
Institutions:Medicine > Lehrstuhl für Innere Medizin II
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.3727/096368916X691646DOI
Keywords:Vascular graft-versus-host disease (GVHD); Indoleamine 2,3-dioxygenase (IDO); Adiponectin (APN); Cytokines
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:35056
Owner only: item control page

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