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A Candidate Gene Association Study Identifies DAPL1 as a Female-Specific Susceptibility Locus for Age-Related Macular Degeneration (AMD)

URN to cite this document:
urn:nbn:de:bvb:355-epub-351252
DOI to cite this document:
10.5283/epub.35125
Grassmann, Felix ; Friedrich, Ulrike ; Fauser, Sascha ; Schick, Tina ; Milenkovic, Andrea ; Schulz, Heidi L. ; von Strachwitz, Claudia N. ; Bettecken, Thomas ; Lichtner, Peter ; Meitinger, Thomas ; Arend, Nicole ; Wolf, Armin ; Haritoglou, Christos ; Rudolph, Guenther ; Chakravarthy, Usha ; Silvestri, Giuliana ; McKay, Gareth J. ; Freitag-Wolf, Sandra ; Krawczak, Michael ; Smith, R. Theodore ; Merriam, John C. ; Merriam, Joanna E. ; Allikmets, Rando ; Heid, Iris M. ; Weber, Bernhard H. F.
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Date of publication of this fulltext: 01 Feb 2017 14:20


Abstract

Age-related macular degeneration (AMD) is the leading cause of blindness among white caucasians over the age of 50 years with a prevalence rate expected to increase markedly with an anticipated increase in the life span of the world population. To further expand our knowledge of the genetic architecture of the disease, we pursued a candidate gene approach assessing 25 genes and a total of 109 ...

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