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Plasmodium falciparum Nucleosomes Exhibit Reduced Stability and Lost Sequence Dependent Nucleosome Positioning

Längst, Gernot, Silberhorn, Elisabeth, Schwartz, Uwe, Löffler, Patrick, Schmitz, Samuel, Symelka, Anne, Koning-Ward, Tania de and Merkl, Rainer (2016) Plasmodium falciparum Nucleosomes Exhibit Reduced Stability and Lost Sequence Dependent Nucleosome Positioning. PLoS Pathogens 12 (12), e10060.

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Date of publication of this fulltext: 10 Feb 2017 07:40

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Other URL: http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1006080


Abstract

The packaging and organization of genomic DNA into chromatin represents an additional regulatory layer of gene expression, with specific nucleosome positions that restrict the accessibility of regulatory DNA elements. The mechanisms that position nucleosomes in vivo are thought to depend on the biophysical properties of the histones, sequence patterns, like phased di-nucleotide repeats and the ...

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Item type:Article
Date:29 December 2016
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Prof. Dr. Gernot Längst
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1371/journal.ppat.1006080DOI
Article-ID: e10060Other
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:35164
Owner only: item control page

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