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Pathopysiology of GvHD and HSCT related complications
Holler, Ernst, Ghimire, Sakhila, Dickinson, Anne M., Weber, Daniela and Marvine, Emily (2017) Pathopysiology of GvHD and HSCT related complications. Alloimmunity and Transplantation 8 (79), pp. 1-24.Date of publication of this fulltext: 10 Feb 2017 11:28
Article
DOI to cite this document: 10.5283/epub.35194
Abstract
For over 60 years, hematopoietic stem cell transplantation (HSCT) has been the major curative therapy for several hematological and genetic disorders, but its efficacy is limited by the secondary disease called graft versus host disease (GvHD). Huge advances have been made in successful transplantation in order to improve patient quality of life and yet, complete success is hard to achieve. This ...
For over 60 years, hematopoietic stem cell transplantation (HSCT) has been the major curative therapy for several hematological and genetic disorders, but its efficacy is limited by the secondary disease called graft versus host disease (GvHD). Huge advances have been made in successful transplantation in order to improve patient quality of life and yet, complete success is hard to achieve. This review assimilates recent updates on pathophysiology of GvHD, prophylaxis and treatment of GvHD related complications and advances in the potential treatment of GvHD.
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Details
| Item type | Article | ||||
| Journal or Publication Title | Alloimmunity and Transplantation | ||||
| Publisher: | Frontiers | ||||
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| Volume: | 8 | ||||
| Number of Issue or Book Chapter: | 79 | ||||
| Page Range: | pp. 1-24 | ||||
| Date | 17 January 2017 | ||||
| Institutions | Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie) | ||||
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| Keywords | allogeneic stem cell transplantation, Graft vs Host Disease, pathophysiology, Treatment, innate immunity and responses, Adaptive Immunity | ||||
| Dewey Decimal Classification | 600 Technology > 610 Medical sciences Medicine | ||||
| Status | Published | ||||
| Refereed | Yes, this version has been refereed | ||||
| Created at the University of Regensburg | Yes | ||||
| URN of the UB Regensburg | urn:nbn:de:bvb:355-epub-351947 | ||||
| Item ID | 35194 |
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