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Holler, Ernst ; Ghimire, Sakhila ; Dickinson, Anne M. ; Weber, Daniela ; Marvine, Emily

Pathopysiology of GvHD and HSCT related complications

Holler, Ernst, Ghimire, Sakhila, Dickinson, Anne M., Weber, Daniela und Marvine, Emily (2017) Pathopysiology of GvHD and HSCT related complications. Alloimmunity and Transplantation 8 (79), S. 1-24.

Veröffentlichungsdatum dieses Volltextes: 10 Feb 2017 11:28
Artikel
DOI zum Zitieren dieses Dokuments: 10.5283/epub.35194


Zusammenfassung

For over 60 years, hematopoietic stem cell transplantation (HSCT) has been the major curative therapy for several hematological and genetic disorders, but its efficacy is limited by the secondary disease called graft versus host disease (GvHD). Huge advances have been made in successful transplantation in order to improve patient quality of life and yet, complete success is hard to achieve. This ...

For over 60 years, hematopoietic stem cell transplantation (HSCT) has been the major curative therapy for several hematological and genetic disorders, but its efficacy is limited by the secondary disease called graft versus host disease (GvHD). Huge advances have been made in successful transplantation in order to improve patient quality of life and yet, complete success is hard to achieve. This review assimilates recent updates on pathophysiology of GvHD, prophylaxis and treatment of GvHD related complications and advances in the potential treatment of GvHD.



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Details

DokumentenartArtikel
Titel eines Journals oder einer ZeitschriftAlloimmunity and Transplantation
Verlag:Frontiers
Band:8
Nummer des Zeitschriftenheftes oder des Kapitels:79
Seitenbereich:S. 1-24
Datum17 Januar 2017
InstitutionenMedizin > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Identifikationsnummer
WertTyp
10.3389/fimmu.2017.00079DOI
Stichwörter / Keywordsallogeneic stem cell transplantation, Graft vs Host Disease, pathophysiology, Treatment, innate immunity and responses, Adaptive Immunity
Dewey-Dezimal-Klassifikation600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin
StatusVeröffentlicht
BegutachtetJa, diese Version wurde begutachtet
An der Universität Regensburg entstandenJa
URN der UB Regensburgurn:nbn:de:bvb:355-epub-351947
Dokumenten-ID35194

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