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Anoctamins in Volume Regulation, Proliferation and Apoptotic Cell Death

Wanitchakool, Podchanart (2017) Anoctamins in Volume Regulation, Proliferation and Apoptotic Cell Death. PhD, Universität Regensburg.

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Date of publication of this fulltext: 14 Feb 2017 11:46

Abstract (English)

The family of anoctamins consists of ten different proteins (called ANO1-10 or TMEM16A-K). A variety of functions have been attributed to anoctamins such as that of Ca2+ activated Cl- channels controlling Cl- secretion, cell volume, cell migration and proliferation, and that of phospholipid scramblases contributing to apoptotic cell death. Some anoctamin members are overexpressed in tumors and ...


Translation of the abstract (German)

Die Anoctamin-Familie besteht aus zehn verschiedenen Proteinen (ANO1-10 oder TMEM16A-K). Inzwischen wurde den Anoctaminen eine Vielzahl von Funktionen zugeordnet. So bilden Anoctamine Ca2+-aktivierte Chloridkanäle, nehmen Einfluß auf das Zellvolumen, die Zellmigration und Zellproliferation und bilden Membranphospholipid-Scramblasen, womit sie einen Beitrag zum apoptotischen Zelltod leisten. ...


Export bibliographical data

Item type:Thesis of the University of Regensburg (PhD)
Date:14 February 2017
Referee:Prof. Dr. Karl Kunzelmann and Prof. Dr. Bernhard Weber and Prof. Dr. Ernst Tamm
Date of exam:21 December 2016
Institutions:Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Karl Kunzelmann
Keywords:Anoctamin family, Volume regulation, RVD, VRAC, Cell proliferation, Apoptosis, Cancer, Innate immunity
Dewey Decimal Classification:500 Science > 500 Natural sciences & mathematics
500 Science > 570 Life sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:35208
Owner only: item control page


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