| Lizenz: Creative Commons Namensnennung 4.0 International PDF - Veröffentlichte Version (2MB) |
- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-352220
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.35222
Zusammenfassung
Proof-of-concept for a successful adeno-associated virus serotype 5 ( AAV5)-mediated gene therapy in X-linked juvenile retinoschisis ( XLRS) has been demonstrated in an established mouse model for this condition. The initial studies concentrated on early time-points of treatment. In this study, we aimed to explore the consequences of single subretinal injections administered at various stages of ...
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