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Conservation of human-derived pseudoautosomal sequences on the sex chromosomes of the great apes

Weber, Bernhard H. F. ; Weissenbach, J. ; Schempp, W.


In situ hybridization using a repeated element specific for the human pseudoautosomal region, DXYZ2, revealed the presence of this repeat in the early replicating portion of the sex chromosomes of the great apes. This segment, as well as the DXYZ2 repeats, are located in band Xp22.3 and in a telomeric or subtelomeric region of the Y chromosome. These segments may therefore represent pseudoautosomal regions, as in man.

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