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Linkage disequilibrium and modification of risk for Huntington disease

Adam, S, Theilmann, J, Buetow, K, Hedrick, A, Collins, C, Weber, Bernhard H. F. , Huggins, M and Hayden, M (1991) Linkage disequilibrium and modification of risk for Huntington disease. The American Journal of Human Genetics 48 (3), pp. 595-603.

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The major limitation in performing predictive testing for Huntington disease (HD) is the unavailability of DNA from crucial family members. In our program approximately 20% (36/183) of persons have been excluded from predictive testing because of this reason. The major aim of this study was to examine whether data derived from linkage disequilibrium could modify risk analysis for persons at risk ...


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Item type:Article
Institutions:Medicine > Lehrstuhl für Humangenetik
Identification Number:
1671809PubMed ID
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Item ID:35293
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