Keller, Max 
, Maschauer, Simone, Brennauer, Albert, Tripal, Philipp, Koglin, Norman, Dittrich, Ralf, Bernhardt, Günther, Kuwert, Torsten, Wester, Hans-Jürgen, Buschauer, Armin and Prante, Olaf
(2017)
Prototypic 18F-Labeled Argininamide-Type Neuropeptide Y Y1R Antagonists as Tracers for PET Imaging of Mammary Carcinoma.
ACS Medicinal Chemistry Letters 8, pp. 304-309.
Full text not available from this repository.
Other URL: http://dx.doi.org/10.1021/acsmedchemlett.6b00467
Abstract
The neuropeptide Y (NPY) Y-1, receptor (Y-1,R) selective radioligand (R)-N-a -(2,2-diphenylacety1)N-omega-[4(2[F-18]fluoropropanoylamino)butyllaminocarbonyl-N-(4-hydroxybenzy1)-argininamide ([F-18]23), derived from the high-affinity Y-1,R antagonist BIBP3226, was developed for imaging studies of Y-1,R-positive tumors. Starting from the argininamide core bearing amine-functionalized spacer ...
Export bibliographical data
| Item type: | Article | ||||||
|---|---|---|---|---|---|---|---|
| Date: | 21 February 2017 | ||||||
| Additional Information (public): | Supporting information available online | ||||||
| Institutions: | Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer) | ||||||
| Projects: | GRK 1910, Graduiertenkolleg "Medicinal Chemistry of Selective GPCR Ligands" | ||||||
| Identification Number: |
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| Keywords: | Y-1 RECEPTOR ANTAGONISTS; ACYLGUANIDINE BIOISOSTERIC APPROACH; POSITRON-EMISSION-TOMOGRAPHY; TARGETED TUMOR-DIAGNOSIS; BREAST-CANCER; PEPTIDE-HORMONES; HIGHLY POTENT; THERAPY; NEUROTENSIN; ANALOGS; Fluorine-18; antagonist; positron emission tomography; PET; neuropeptide Y; NPY; Y1R | ||||||
| Dewey Decimal Classification: | 500 Science > 540 Chemistry & allied sciences | ||||||
| Status: | Published | ||||||
| Refereed: | Yes, this version has been refereed | ||||||
| Created at the University of Regensburg: | Partially | ||||||
| Item ID: | 35318 |
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