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Identification of novel TP53 mutations in familial and sporadic cancer cases of German and Swiss origin

Bendig, I, Mohr, N, Krämer, F and Weber, Bernhard H. F. (2004) Identification of novel TP53 mutations in familial and sporadic cancer cases of German and Swiss origin. Cancer Genetics and Cytogenetics 154 (1), pp. 22-26.

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Abstract

Li-Fraumeni Syndrome (LFS) is a rare cancer syndrome caused by mutations in the TP53 gene. A number of tumor-associated germline mutations have been described in individuals from various ethnic origins although, thus far, none in affected individuals of German descent. Our work aimed to detect germline mutations in the TP53 gene in five index cases of German and Swiss origin with cancers typical ...

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Item type:Article
Date:2004
Institutions:Medicine > Lehrstuhl für Humangenetik
Identification Number:
ValueType
10.1016/S0165-4608(97)00285-9DOI
15381368PubMed ID
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Item ID:35545
Owner only: item control page
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