Weissert, Robert and ‘t Hart, Bert A.
(2016)
Myelin oligodendrocyte glycoprotein has a dual role in T cell autoimmunity against central nervous system myelin.
Multiple Sclerosis Journal – Experimental, Translational and Clinical 2, pp. 1-5.
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Abstract
Background Myelin oligodendrocyte glycoprotein (MOG) is a candidate primary target of the autoimmune attack on the central nervous system (CNS) in multiple sclerosis (MS). However, the physiological function of MOG has been unclear for a long time. Objective We propose that MOG has a central role in the regulation of tolerance and autoimmunity. Conclusion The interaction of MOG with DC-SIGN, an ...

Export bibliographical data
Item type: | Article | ||||
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Date: | 2016 | ||||
Institutions: | Medicine > Lehrstuhl für Neurologie | ||||
Identification Number: |
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Keywords: | Multiple sclerosis, antigen-presenting cells, tolerance, autoantigen, glycosylation, danger, regulation | ||||
Dewey Decimal Classification: | 600 Technology > 610 Medical sciences Medicine | ||||
Status: | Published | ||||
Refereed: | Yes, this version has been refereed | ||||
Created at the University of Regensburg: | Yes | ||||
Item ID: | 35617 |