The Role of Cyclooxygenase-1 and -2 in Sevoflurane-Induced Postconditioning Against Myocardial Infarction

URN to cite this document:: urn:nbn:de:bvb:355-epub-356523
DOI to cite this document:: 10.5283/epub.35652

Stumpner, J. ; Tischer-Zeitz, T. ; Frank, Anja ; Lotz, Christopher ; Redel, Andreas

Preview

License: Allianz- bzw. Nationallizenz
PDF - Published Version
(543kB)

Date of publication of this fulltext: 11 May 2017 13:43

Alternative links to fulltext:DOI

Details

Preview

Export bibliographical data

Abstract

Cyclooxygenase (COX)-2 mediates ischemic pre- and postconditioning as well as anesthetic-induced preconditioning. However, the role of COX-1 and -2 in anesthetic-induced postconditioning has not been investigated. We evaluated the role of COX-1 and -2 in sevoflurane-induced postconditioning in vivo. Pentobarbital-anaesthetized male C57BL/6 mice were subjected to 45 minutes of coronary artery ...