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Association between a gene variant near ataxia telangiectasia mutated and coronary artery disease in men

URN to cite this document:
urn:nbn:de:bvb:355-epub-356644
Schiekofer, Stephan ; Bobak, I. ; Kleber, M. E. ; März, Winfried ; Rudofsky, G. ; Dugi, K. A. ; Schneider, Jochen A.
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Date of publication of this fulltext: 16 May 2017 11:25


Abstract

Objective: Type 2 diabetes is accompanied by increased mortality from coronary artery disease (CAD), but the mechanisms linking these conditions remain elusive. Hence, treatment of hyperglycaemia alone is not sufficient to avoid CAD in diabetes. Alternative views suggest that metabolic and vascular diseases share unifying cellular defects that could serve as targets for novel therapeutic ...

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