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Hydrogels for the Controlled Release of Protein Pharmaceuticals

Hammer, Nadine (2017) Hydrogels for the Controlled Release of Protein Pharmaceuticals. PhD, Universität Regensburg.

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Date of publication of this fulltext: 31 May 2017 07:56

Abstract (English)

The goal of the thesis was to develop hydrogels as depot formulations for the controlled delivery of protein drugs at the target site. To investigate release profiles, protein compatibility and side reactions a commercial available model protein was used. Due to its well characterized structure and properties, lysozyme is ideally suited as model drug. A further advantage of lysozyme is the ...

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Translation of the abstract (German)

Das Ziel dieser Arbeit war die Entwicklung von Hydrogelen als Depotformulierung um eine kontrollierte Protein-Freisetzung direkt am Wirkort zu erzielen. Dabei wurde Lysozym als ein kommerziell erhältliches Modelprotein verwendet um Freisetzungsprofile, Proteinkompatibilität und Nebenreaktionen zu untersuchen. Lysozym ist ein idealer Modelwirkstoff, da seine Struktur und Eigenschaften ausführlich ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:31 May 2017
Referee:Prof. Dr. Achim Göpferich and Prof. Dr. Torsten Blunk
Date of exam:15 May 2017
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich)
Keywords:hydrogels, controlled release, proteins, drug delivery
Dewey Decimal Classification:500 Science > 500 Natural sciences & mathematics
600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:35677
Owner only: item control page

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