Go to content
UR Home

Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

Couch, F J, Wang, X, McGuffog, L, Lee, A, Olswold, C, Kuchenbaecker, K B, Soucy, P, Weber, Bernhard H. F. and et al, . (2013) Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. PLoS Genetics 9 (3), e1003212.

[img]
Preview
PDF
Download (3MB)
Date of publication of this fulltext: 07 Jul 2017 11:47

at publisher (via DOI)

at PubMed

Other URL: http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1003212


Abstract

BRCA1-associated breast and ovarian cancer risks can be modified by common genetic variants. To identify further cancer risk-modifying loci, we performed a multi-stage GWAS of 11,705 BRCA1 carriers (of whom 5,920 were diagnosed with breast and 1,839 were diagnosed with ovarian cancer), with a further replication in an additional sample of 2,646 BRCA1 carriers. We identified a novel breast cancer ...

plus


Export bibliographical data



Item type:Article
Date:2013
Institutions:Medicine > Lehrstuhl für Humangenetik
Identification Number:
ValueType
10.1371/journal.pgen.1003212DOI
23544013PubMed ID
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:35861
Owner only: item control page

Downloads

Downloads per month over past year

  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons