Reinhard, J. ; Messias, A. ; Dietz, K. ; Mackeben, M. ; Lakmann, R. ; Scholl, H. P. ; Apfelstedt-Sylla, E. ; Weber, Bernhard H. F.
; Seeliger, M. W. ; Zrenner, E. ; Trauzettel-Klosinski, S.
Alternative Links zum Volltext:DOIPubmed
Dokumentenart: | Artikel |
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Titel eines Journals oder einer Zeitschrift: | Vision Research |
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Verlag: | Elsevier |
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Band: | 47 |
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Nummer des Zeitschriftenheftes oder des Kapitels: | 15 |
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Seitenbereich: | S. 2076-2085 |
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Datum: | 2007 |
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Institutionen: | Medizin > Lehrstuhl für Humangenetik |
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Identifikationsnummer: | Wert | Typ |
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10.1016/j.visres.2007.04.012 | DOI | 17562343 | PubMed-ID |
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Dewey-Dezimal-Klassifikation: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin |
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Status: | Veröffentlicht |
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Begutachtet: | Ja, diese Version wurde begutachtet |
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An der Universität Regensburg entstanden: | Zum Teil |
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Dokumenten-ID: | 35926 |
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Zusammenfassung
Fixational eye movements in 60 eyes of 30 patients with ABCA4-associated Stargardt disease were recorded by a Scanning Laser Ophthalmoscope (SLO). The results were quantified by two new fixation quality measures expressing the eccentricity of the preferred retinal locus (PRL) non-parametrically, and fixation stability by a dynamic index. 46 eyes (77%) fixated eccentrically; in 32 eyes (70% of the ...
Zusammenfassung
Fixational eye movements in 60 eyes of 30 patients with ABCA4-associated Stargardt disease were recorded by a Scanning Laser Ophthalmoscope (SLO). The results were quantified by two new fixation quality measures expressing the eccentricity of the preferred retinal locus (PRL) non-parametrically, and fixation stability by a dynamic index. 46 eyes (77%) fixated eccentrically; in 32 eyes (70% of the eccentrically fixating eyes) the PRL was located above the central retinal lesion. PRL eccentricity correlated positively with logMAR visual acuity (r = .72; p < .0001) and negatively with fixation stability (r = −.58; p < .0001). Multiple PRL were found only in three eyes.