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Genetic variants within miR-126 and miR-335 are not associated with breast cancer risk

Yang, R, Dick, M, Marme, F, Schneeweiss, A, Langheinz, A, Hemminki, K, Sutter, C, Bugert, P, Wappenschmidt, B, Varon, R, Schott, S, Weber, Bernhard H. F. , Niederacher, D, Arnold, N, Meindl, A, Bartram, C R, Schmutzler, R K, Müller, H, Arndt, V, Brenner, H, Sohn, C and Burwinkel, B (2011) Genetic variants within miR-126 and miR-335 are not associated with breast cancer risk. Breast Cancer Research and Treatment 127 (2), pp. 549-554.

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Abstract

MicroRNAs (miRNAs) are 20–22 nt non-coding RNAs which promote the degradation of target mRNAs or repression of the translation of mRNAs by sequence specific targeting. Many miRNAs are considered as oncogenes or tumor suppressors. MiR-126 and miR-335 play roles in the suppression of breast cancer metastasis by inhibiting tumor growth, proliferation, and cell invasion. The effects of SNPs within ...

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Item type:Article
Date:2011
Institutions:Medicine > Lehrstuhl für Humangenetik
Identification Number:
ValueType
10.1007/s10549-010-1244-xDOI
Keywords:Breast cancer, Polymorphism, miRNA, Genetic variants, SNP
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:36017
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