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Characterization of Enzymes Involved in the Synthesis and Processing of Ether Lipids in Archaea and Bacteria

Linde, Mona (2017) Characterization of Enzymes Involved in the Synthesis and Processing of Ether Lipids in Archaea and Bacteria. PhD, Universität Regensburg.

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Date of publication of this fulltext: 26 Jul 2017 09:05

Abstract (English)

In Archaea, ether lipids play an essential role as the main building blocks of the cellular membrane. Recently, ether lipids have also been discovered in the domain of Bacteria, and the key enzymes that catalyze their synthesis, glycerol 1-phosphate dehydrogenase (AraM) and heptaprenylglyceryl phosphate synthase (HepGPS), have been described. In Bacillales, heptaprenylglyceryl phosphate (HepGP) ...

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Translation of the abstract (German)

Etherlipide spielen in Archaeen eine essentielle Rolle als Hauptbausteine der Zellmembran. Kürzlich wurden auch in Bakterien Etherlipide entdeckt und die Schlüsselenzyme, die deren Synthese katalysieren identifiziert: die Glycerin-1-phosphatdehydrogenase (AraM) und die Heptaprenylglycerinphosphatsynthase (HepGPS). In Bacillales wird das entstandene Heptaprenylglycerinphosphat (HepGP) jedoch nicht ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:26 July 2017
Referee:Prof. Dr. Reinhard Sterner and Prof. Dr. Werner Kremer and Prof. Dr. Christine Ziegler
Date of exam:22 June 2017
Institutions:Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Reinhard Sterner
Keywords:ether lipids, Archaea, geranylgeranylglyceryl phosphate synthase, oligomerization
Dewey Decimal Classification:500 Science > 500 Natural sciences & mathematics
500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:36036
Owner only: item control page

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