Effect of EpCAM, CD44, CD133 and CD166 expression on patient survival in tumours of the ampulla of Vater

URN to cite this document:: urn:nbn:de:bvb:355-epub-361385
DOI to cite this document:: 10.5283/epub.36138

Piscuoglio, Salvatore ; Lehmann, Frank S. ; Zlobec, I. ; Dietmaier, Wolfgang ; Rümmele, Petra

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Date of publication of this fulltext: 04 Sep 2017 09:38

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Abstract

Background: Carcinomas of the Vaterian system are rare and presumably arise from pre-existing adenomas. According to the cancer stem cell (CSC) hypothesis, only a small subset of tumor cells has the ability to initiate and develop tumor growth. In colorectal cancer, CD44, CD133, CD166 and EpCAM have been proposed to represent CSC marker proteins and their expression has been shown to correlate ...