Adiponectin isoforms: a potential therapeutic target in rheumatoid arthritis?

URN to cite this document:: urn:nbn:de:bvb:355-epub-361529
DOI to cite this document:: 10.5283/epub.36152

Frommer, K. W. ; Schäffler, Andreas ; Büchler, Christa ; Steinmeyer, J. ; Rickert, M. ; Rehart, S. ; Brentano, F. ; Gay, Steffen ; Müller-Ladner, Ulf ; Neumann, Elena

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Date of publication of this fulltext: 05 Sep 2017 13:27

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Abstract

Objectives: Several clinical studies have suggested the adipocytokine adiponectin is involved in the progression of rheumatoid arthritis (RA). From this point of view, adiponectin might present a new therapeutic target. However, as adiponectin also exerts beneficial effects in the human organism, a strategy that would allow its detrimental effects to be abolished while maintaining the positive ...