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Neutrophil microvesicles resolve gout by inhibiting C5a-mediated priming of the inflammasome

Cumpelik, A., Ankli, B. and Zecher, Daniel (2016) Neutrophil microvesicles resolve gout by inhibiting C5a-mediated priming of the inflammasome. Annals of the Rheumatic Diseases 75, pp. 1236-1245.

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Date of publication of this fulltext: 03 Nov 2017 10:49

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Abstract

Objectives Gout is a highly inflammatory but self-limiting joint disease induced by the precipitation of monosodium urate (MSU) crystals. While it is well established that inflammasome activation by MSU mediates acute inflammation, little is known about the mechanism controlling its spontaneous resolution. The aim of this study was to analyse the role of neutrophil-derived microvesicles ...

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Item type:Article
Date:2016
Institutions:Medicine > Lehrstuhl für Innere Medizin II
Identification Number:
ValueType
10.1136/annrheumdis-2015-207338DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:36295
Owner only: item control page

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